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Variance in size can often be attributed to de novo mutations.Deficiency of pituitary growth hormone or gonadotropins or mild degrees of androgen insensitivity can cause small penis size in males and can be addressed with growth hormone or testosterone treatment in early childhood.Human penises vary in size on a number of measures, including length and circumference when flaccid and erect.

The average stretched penile length at birth is about 4 cm (1.6 in), and 90% of newborn boys will be between 2.4 and 5.5 cm (0.94 and 2.17 in). Authors of a paper reviewing research on area of penis sizes conclude that "flaccid penile length is just under 4 cm (1.6 in) at birth and changes very little until puberty, when there is marked growth." Age is not believed to negatively correlate with penis size. suggested that penis size is smaller in studies focusing on older men, but Wylie and Eardley found no overall differences when they collated the results of various studies [over a 60 year period]." A 2015 review of the literature found two studies finding height and stretched or flaccid length to be moderately correlated, seven studies finding weak correlation for flaccid, stretched, or erect length, and two studies that found no correlation between flaccid length and height.

As a witty satire of this fantasy, the 9th-century Afro-Arab author Al-Jahiz wrote: "If the length of the penis were a sign of honor, then the mule would belong to the Quraysh" (the tribe to which Muhammad belonged and from which he descended).

and a thirteenth-century Norse magic talisman from Bergen, a wooden stave inscribed with writing in runic script, promises its wearer: "You will fuck Rannveig the Red.

Compared to other primates, including large examples such as the gorilla, the human penis is thickest, both in absolute terms and relative to the rest of the body.

Measurements vary, with studies that rely on self-measurement reporting a significantly higher average than those with a health professional measuring.

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